PKNCA - Perform Pharmacokinetic Non-Compartmental Analysis

Compute standard Non-Compartmental Analysis (NCA) parameters for typical pharmacokinetic analyses and summarize them.

Last updated 18 days ago

ncanoncompartmental-analysispharmacokinetics

12.55 score 73 stars 4 dependents 214 scripts 1.8k downloads

nlmixr2lib - A Model Library for 'nlmixr2'

A model library for 'nlmixr2'. The models include (and plan to include) pharmacokinetic, pharmacodynamic, and disease models used in pharmacometrics. Where applicable, references for each model are included in the meta-data for each individual model. The package also includes model composition and modification functions to make model updates easier.

Last updated 2 months ago

6.38 score 6 stars 9 scripts 357 downloads

ggtibble - Create Tibbles and Lists of 'ggplot' Figures for Reporting

Create tibbles and lists of 'ggplot' figures that can be modified as easily as regular 'ggplot' figures. Typical use cases are for creating reports or web pages where many figures are needed with different data and similar formatting.

Last updated 21 days ago

4.95 score 2 stars 3 scripts 170 downloads

hidradenitis - Calculate Clinical Scores for Hidradenitis Suppurativa (HS), a Dermatologic Disease

Calculate clinical scores for hidradenitis suppurativa (HS), a dermatologic disease. The scores are typically used for evaluation of efficacy in clinical trials. The scores are not commonly used in clinical practice. The specific scores implemented are Hidradenitis Suppurativa Clinical Response (HiSCR) (Kimball, et al. (2015) <doi:10.1111/jdv.13216>), Hidradenitis Suppurativa Area and Severity Index Revised (HASI-R) (Goldfarb, et al. (2020) <doi:10.1111/bjd.19565>), hidradenitis suppurativa Physician Global Assessment (HS PGA) (Marzano, et al. (2020) <doi:10.1111/jdv.16328>), and the International Hidradenitis Suppurativa Severity Score System (IHS4) (Zouboulis, et al. (2017) <doi:10.1111/bjd.15748>).

Last updated 2 months ago

3.95 score 1 stars 2 scripts 259 downloads

equil2 - Calculate Urinary Saturation with the EQUIL2 Algorithm

Saturation of ionic substances in urine is calculated based on sodium, potassium, calcium, magnesium, ammonia, chloride, phosphate, sulfate, oxalate, citrate, ph, and urate. This program is intended for research use, only. The code within is translated from EQUIL2 Visual Basic code based on Werness, et al (1985) "EQUIL2: a BASIC computer program for the calculation of urinary saturation" <doi:10.1016/s0022-5347(17)47703-2> to R. The Visual Basic code was kindly provided by Dr. John Lieske of the Mayo Clinic.

Last updated 2 years ago

3.70 score 4 scripts 213 downloads

nlmixr2targets - Targets for 'nlmixr2' Pipelines

'nlmixr2' often has long runtimes. A pipeline toolkit tailored to 'nlmixr2' workflows leverages 'targets' and 'nlmixr2' to ease reproducible workflows. 'nlmixr2targets' ensures minimal rework in model development with 'nlmixr2' and 'targets' by simplifying and standardizing models and datasets.

Last updated 3 days ago

3.18 score 6 scripts

geboes.score - Evaluate the Geboes Score for Histology in Ulcerative Colitis

Evaluate and validate the Geboes score for histological assessment of inflammation in ulcerative colitis. The original Geboes score from Geboes, et al. (2000) <doi:10.1136/gut.47.3.404>, binary version from Li, et al. (2019) <doi:10.1093/ecco-jcc/jjz022>, and continuous version from Magro, et al. (2020) <doi:10.1093/ecco-jcc/jjz123> are all described and implemented.

Last updated 7 months ago

3.18 score 2 scripts 198 downloads

formulops - Mathematical Operations on R Formula

Perform mathematical operations on R formula (add, subtract, multiply, etc.) and substitute parts of formula.

Last updated 29 days ago

2.70 score 1 stars 204 downloads